This session showcases the Peer-to-Peer Prevention Program (PPPP), a collaborative pilot project of Community Matters and Santa Clara Department of Alcohol and Drug Services (California, USA). The PPPP offers an innovative approach to preventing youth use of alcohol and other drugs (AOD), an approach that aims to decrease student use of AODs through peer-to-peer interventions and the shifting of norms. The PPPP follows the framework of the evidenced-based National Registry of Evidence-Based Programs and Practices (NREPP)-listed Safe School Ambassador Program (SSA), which has resulted in decreased bullying and school violence-related suspensions. Like the SSA Program, the Peer-to-Peer Prevention Program engages social leaders and trains them in techniques that address the use of AODs in the student population. Students are equipped with the knowledge and motivation to speak up against substance use among their friends and peers. This is accomplished by educating teens about why it is important to support friends and peers in making healthy choices and how best to do that. In the training, students learn safe and effective interventions that allow them to retain status and credibility while promoting healthier decisions by their peers. Over time, these interventions can create a shift in the school norms where substance use will not be supported.